Recombinant Mouse Pdgfb protein, His/S-tagged

Cat.No. : Pdgfb-172M
Product Overview : Recombinant Mouse Pdgfb fused with His/S tag was expressed in E. coli.
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Species : Mouse
Source : E.coli
Tag : His&S
Description : Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.
Form : Lyophilized from sterile PBS, pH 7.4
Purity : > 95 % as determined by SDS-PAGE
Storage : Store at -70 centigrade. Avoid repeated freeze/thaw cycles.
Gene Name Pdgfb platelet derived growth factor, B polypeptide [ Mus musculus ]
Official Symbol Pdgfb
Synonyms PDGFB; platelet derived growth factor, B polypeptide; platelet-derived growth factor subunit B; c-sis; PDGF-2; PDGF subunit B; proto-oncogene c-Sis; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; Sis; PDGF-B;
Gene ID 18591
mRNA Refseq NM_011057
Protein Refseq NP_035187
UniProt ID P31240
Chromosome Location 15 E1; 15 37.85 cM
Pathway Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signal transduction, organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem;
Function cell surface binding; collagen binding; eukaryotic cell surface binding; growth factor activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity; superoxide-generating NADPH oxidase activator activity;

Not For Human Consumption!

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