Recombinant Mouse Pdgfb protein, His/S-tagged
Cat.No. : | Pdgfb-172M |
Product Overview : | Recombinant Mouse Pdgfb fused with His/S tag was expressed in E. coli. |
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Species : | Mouse |
Source : | E.coli |
Tag : | His&S |
Description : | Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family. |
Form : | Lyophilized from sterile PBS, pH 7.4 |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Store at -70 centigrade. Avoid repeated freeze/thaw cycles. |
Gene Name | Pdgfb platelet derived growth factor, B polypeptide [ Mus musculus ] |
Official Symbol | Pdgfb |
Synonyms | PDGFB; platelet derived growth factor, B polypeptide; platelet-derived growth factor subunit B; c-sis; PDGF-2; PDGF subunit B; proto-oncogene c-Sis; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; Sis; PDGF-B; |
Gene ID | 18591 |
mRNA Refseq | NM_011057 |
Protein Refseq | NP_035187 |
UniProt ID | P31240 |
Chromosome Location | 15 E1; 15 37.85 cM |
Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signal transduction, organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; |
Function | cell surface binding; collagen binding; eukaryotic cell surface binding; growth factor activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity; superoxide-generating NADPH oxidase activator activity; |
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Not For Human Consumption!
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