Recombinant Mouse Pdgfb protein, His/S-tagged

• Cat.No.: Pdgfb-172M
• Product Overview: Recombinant Mouse Pdgfb fused with His/S tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His&S
• Description: Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.
• Form: Lyophilized from sterile PBS, pH 7.4
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Store at -70 centigrade. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: Pdgfb platelet derived growth factor, B polypeptide [ Mus musculus ]
• Official Symbol: Pdgfb
• Synonyms: PDGFB; platelet derived growth factor, B polypeptide; platelet-derived growth factor subunit B; c-sis; PDGF-2; PDGF subunit B; proto-oncogene c-Sis; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; Sis; PDGF-B
• Gene ID: 18591
• mRNA Refseq: NM_011057
• Protein Refseq: NP_035187
• UniProt ID: P31240
• Chromosome Location: 15 E1; 15 37.85 cM
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signal transduction, organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem
• Function: cell surface binding; collagen binding; eukaryotic cell surface binding; growth factor activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity; superoxide-generating NADPH oxidase activator activity