Recombinant Mouse Pde3b Protein, Myc/DDK-tagged

• Cat.No.: Pde3b-4744M
• Product Overview: Purified recombinant protein of mouse full-length phosphodiesterase 3B, cGMP-inhibited (Pde3b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
• Molecular Mass: 122.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pde3b phosphodiesterase 3B, cGMP-inhibited [ Mus musculus (house mouse) ]
• Official Symbol: Pde3b
• Synonyms: PDE3B; phosphodiesterase 3B, cGMP-inhibited; cGMP-inhibited 3,5-cyclic phosphodiesterase B; CGIPDE1; CGI-PDE B; cyclic GMP-inhibited phosphodiesterase B; AI847709; 9830102A01Rik
• Gene ID: 18576
• mRNA Refseq: NM_011055
• Protein Refseq: NP_035185
• UniProt ID: Q61409