Recombinant Mouse Pdcd1 Protein (Leu25-Gln167), C-His tagged

• Cat.No.: Pdcd1-6766M
• Product Overview: Recombinant mouse PDCD1 (Leu25-Gln167) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Description: Involved in negative regulation of immune response. Acts upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in external side of plasma membrane. Is expressed in retina. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog (s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1).
• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 15.73 kDa
• Protein length: Leu25-Gln167
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Pdcd1 programmed cell death 1 [ Mus musculus (house mouse) ]
• Official Symbol: Pdcd1
• Synonyms: PDCD1; programmed cell death 1; programmed cell death protein 1; mPD-1; protein PD-1; PD-1; Pdc1; Ly101
• Gene ID: 18566
• mRNA Refseq: NM_008798
• Protein Refseq: NP_032824
• UniProt ID: Q02242