Recombinant Mouse Oxt Protein, Myc/DDK-tagged

Cat.No. : Oxt-4634M
Product Overview : Purified recombinant protein of mouse full-length oxytocin (Oxt), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Species : Mouse
Source : HEK293
Tag : DDK&Myc
Description : This gene encodes a preproprotein that is processed to produce oxytocin and neurophysin 1. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin 1. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation, the stress response and complex sexual and maternal behavior, as well as in the regulation of water excretion, salt appetite, blood pressure and cardiovascular functions. Deletion of this gene in mouse reduces bone formation resulting in osteoporosis.
Molecular Mass : 13.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Oxt oxytocin [ Mus musculus (house mouse) ]
Official Symbol Oxt
Synonyms OXT; oxytocin; oxytocin-neurophysin 1; OT-NPI; OT; Oxy
Gene ID 18429
mRNA Refseq NM_011025
Protein Refseq NP_035155
UniProt ID P35454

Not For Human Consumption!

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