Recombinant Mouse Otud5 Protein, Myc/DDK-tagged

• Cat.No.: Otud5-4627M
• Product Overview: Purified recombinant protein of mouse full-length OTU domain containing 5 (Otud5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).
• Molecular Mass: 60.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Otud5 OTU domain containing 5 [ Mus musculus (house mouse) ]
• Official Symbol: Otud5
• Synonyms: Otud5; OTU domain containing 5; Dub; Sfc; DUBA; Sfc7; DXImx46; AA407879; AI553596; BB114028; DXImx46e; OTU domain-containing protein 5; deubiquinating enzyme A; deubiquitinating enzyme A; EC 3.4.19.12
• Gene ID: 54644
• mRNA Refseq: NM_138604
• Protein Refseq: NP_613070
• UniProt ID: Q3U2S4