Recombinant Mouse Osbp Protein, Myc/DDK-tagged

Cat.No. : Osbp-4606M
Product Overview : Purified recombinant protein of mouse full-length oxysterol binding protein (Osbp), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Species : Mouse
Source : HEK293
Tag : DDK&Myc
Description : Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability.
Molecular Mass : 89.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Osbp oxysterol binding protein [ Mus musculus (house mouse) ]
Official Symbol Osbp
Synonyms OSBP; oxysterol binding protein; oxysterol-binding protein 1; AW559088; mKIAA4220; 1110018F06Rik; KIAA4220
Gene ID 76303
mRNA Refseq NM_001033174
Protein Refseq NP_001028346
UniProt ID Q3B7Z2

Not For Human Consumption!

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