Recombinant Mouse Osbp Protein, Myc/DDK-tagged
Cat.No. : | Osbp-4606M |
Product Overview : | Purified recombinant protein of mouse full-length oxysterol binding protein (Osbp), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability. |
Molecular Mass : | 89.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Osbp oxysterol binding protein [ Mus musculus (house mouse) ] |
Official Symbol | Osbp |
Synonyms | OSBP; oxysterol binding protein; oxysterol-binding protein 1; AW559088; mKIAA4220; 1110018F06Rik; KIAA4220 |
Gene ID | 76303 |
mRNA Refseq | NM_001033174 |
Protein Refseq | NP_001028346 |
UniProt ID | Q3B7Z2 |
◆ Recombinant Proteins | ||
OSBP-8006H | Recombinant Human OSBP protein, His & T7-tagged | +Inquiry |
OSBP-1587H | Recombinant Human OSBP Protein, His (Fc)-Avi-tagged | +Inquiry |
OSBP-7336Z | Recombinant Zebrafish OSBP | +Inquiry |
OSBP-3250R | Recombinant Rhesus monkey OSBP Protein, His-tagged | +Inquiry |
OSBP-3068R | Recombinant Rhesus Macaque OSBP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
OSBP-3544HCL | Recombinant Human OSBP 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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