Recombinant Mouse Nosip Protein, Myc/DDK-tagged

• Cat.No.: Nosip-4463M
• Product Overview: Purified recombinant protein of mouse full-length nitric oxide synthase interacting protein (Nosip), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
• Molecular Mass: 33.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nosip nitric oxide synthase interacting protein [ Mus musculus (house mouse) ]
• Official Symbol: Nosip
• Synonyms: NOSIP; nitric oxide synthase interacting protein; nitric oxide synthase-interacting protein; CGI-25; 2310061K06Rik; MGC115777
• Gene ID: 66394
• mRNA Refseq: NM_025533
• Protein Refseq: NP_079809
• UniProt ID: Q9D6T0