Recombinant Mouse Noggin

• Cat.No.: Nog-1770M

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Description: Noggin is a secreted glycoprotein predominantly expressed by the dorsal mesoderm during embryogenesis that inhibits TGF-β signal transduction by binding to TGF-β family ligands and preventing them from binding to their corresponding receptors.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse Nog is Mr 26 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 30 - 35 kDa.
• State Of Matter: Lyophilized.
• Formulation: This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: Nog noggin [ Mus musculus ]
• Synonyms: Nog; noggin; OTTMUSP00000001311
• Gene ID: 18121
• mRNA Refseq: NM_008711
• Protein Refseq: NP_032737
• UniProt ID: P97466
• Chromosome Location: 11 C; 11 50.5 cM
• Pathway: TGF-beta signaling pathway