Recombinant Mouse Nkrf Protein, Myc/DDK-tagged

• Cat.No.: Nkrf-4423M
• Product Overview: Purified recombinant protein of mouse full-length NF-kappaB repressing factor (Nkrf), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
• Molecular Mass: 77.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nkrf NF-kappaB repressing factor [ Mus musculus (house mouse) ]
• Official Symbol: Nkrf
• Synonyms: NKRF; NF-kappaB repressing factor; NF-kappa-B-repressing factor; NFkB-repressing factor; transcription factor NRF; C80287; AW124770; 9430034D17Rik
• Gene ID: 77286
• mRNA Refseq: NM_029891
• Protein Refseq: NP_084167
• UniProt ID: Q8BY02