NKRF
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Official Full Name
NFKB repressing factor -
Overview
This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. -
Synonyms
NKRF;NFKB repressing factor;NF kappaB repressing factor;NF-kappa-B-repressing factor;ITBA4;NRF;OTTHUMP00000023906;OTTHUMP00000023907;transcription factor NRF
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&GST
- Non
- His&Fc&Avi
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NKRF-1302H | Recombinant Human NKRF, His-tagged | E.coli | Human | His | 345-690aa | |
| NKRF-783H | Recombinant Human NKRF Protein, His/GST-tagged | E.coli | Human | His&GST | Met1~Val296 | |
| NKRF-10695M | Recombinant Mouse NKRF Protein | Mammalian Cells | Mouse | His |
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| NKRF-1244Z | Recombinant Zebrafish NKRF | Mammalian Cells | Zebrafish | His |
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| NKRF-2102C | Recombinant Chicken NKRF | Mammalian Cells | Chicken | His |
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| NKRF-29050TH | Recombinant Human NKRF, His-tagged | E.coli | Human | His | 299-690 a.a. |
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| NKRF-3036R | Recombinant Rhesus monkey NKRF Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| NKRF-3815HCL | Recombinant Human NKRF 293 Cell Lysate | HEK293 | Human | Non |
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| NKRF-2855R | Recombinant Rhesus Macaque NKRF Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| NKRF-2855R-B | Recombinant Rhesus Macaque NKRF Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| NKRF-3276H | Recombinant Human NKRF protein, His-tagged | E.coli | Human | His | 4-688aa |
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| Nkrf-4423M | Recombinant Mouse Nkrf Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| NKRF-5893H | Recombinant Human NKRF Protein, GST-tagged | Wheat Germ | Human | GST |
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| NKRF-6083M | Recombinant Mouse NKRF Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NKRF-6083M-B | Recombinant Mouse NKRF Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| NKRF-6670HF | Recombinant Full Length Human NKRF Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 690 amino acids |
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Involved Pathway
NKRF involved in several pathways and played different roles in them. We selected most pathways NKRF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKRF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NKRF has several biochemical functions, for example, DNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKRF itself. We selected most functions NKRF had, and list some proteins which have the same functions with NKRF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZFP110,PHTF1,BSX,TRIM16,ANO9A,ZNF571,DNASE1L2,ZFP521,NEUROD4,BEND5 |
| protein binding | ASCC1,RABL2A,RARRES3,NDRG1,LPAL2,PFTK1,ATP1B1,ENTPD1,RAB24,SF1 |
| poly(A) RNA binding | AGO1,WDR6,C11orf68,BRIX1,PTPN1,EIF1AX,POP7,YTHDC2,SYNCRIP,MYBBP1A |
Interacting Protein
NKRF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKRF here. Most of them are supplied by our site. Hope this information will be useful for your research of NKRF.
DHX58;LRRK2;GAMMAHV.ORF42;PRKRA;HMOX2;Srp72;NS;GABARAP;NPM1;BCL6;MNDA;Nfyc;HNRNPU;LGALS3BP;IFI16;Rpl35;ESR2;Rrbp1
Resources
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References
- Bisio, A; Zamborszky, J; et al. Cooperative interactions between p53 and NF kappa B enhance cell plasticity. ONCOTARGET 5:12111-12125(2014).
- Huang, HY; Joseph, LC; et al. Extracellular signal-regulated kinase activation during cardiac hypertrophy reduces sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) transcription. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 75:58-63(2014).
