Recombinant Mouse Ndrg4 Protein, Myc/DDK-tagged

• Cat.No.: Ndrg4-4326M
• Product Overview: Purified recombinant protein of mouse full-length N-myc downstream regulated gene 4 (Ndrg4), transcript variant B, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress. May enhance growth factor-induced ERK1 and ERK2 phosphorylation. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 37.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ndrg4 N-myc downstream regulated gene 4 [ Mus musculus (house mouse) ]
• Official Symbol: Ndrg4
• Synonyms: NDRG4; N-myc downstream regulated gene 4; protein NDRG4; protein Ndr4; N-myc downstream regulated 1, related sequence; Ndr4; R74996; SMAP-8; Ndr1-rs; D8Bwg1337e; MGC7067
• Gene ID: 234593
• mRNA Refseq: NM_145602
• Protein Refseq: NP_663577
• UniProt ID: Q8BTG7