Recombinant Mouse Morc3 Protein, Myc/DDK-tagged

• Cat.No.: Morc3-4113M
• Product Overview: Purified recombinant protein of mouse full-length microrchidia 3 (Morc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.
• Molecular Mass: 107 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Morc3 microrchidia 3 [ Mus musculus (house mouse) ]
• Official Symbol: Morc3
• Synonyms: MORC3; microrchidia 3; zinc finger, CW-type with coiled-coil domain 3; NXP2; Zcwcc3; AI452146; BF318192; D16Jhu32e; 1110051N18Rik
• Gene ID: 338467
• mRNA Refseq: NM_001045529
• Protein Refseq: NP_001038994
• UniProt ID: F7BJB9