Recombinant Mouse Mme Protein, Myc/DDK-tagged

• Cat.No.: Mme-4097M
• Product Overview: Purified recombinant protein of mouse full-length membrane metallo endopeptidase (Mme), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
• Molecular Mass: 86.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mme membrane metallo endopeptidase [ Mus musculus (house mouse) ]
• Official Symbol: Mme
• Synonyms: MME; membrane metallo endopeptidase; neprilysin; enkephalinase; atriopeptidase; skin fibroblast elastase; neutral endopeptidase 24.11; common acute lymphoblastic leukemia antigen; NEP; SFE; CD10; CALLA; C85356; 6030454K05Rik
• Gene ID: 17380
• mRNA Refseq: NM_008604
• Protein Refseq: NP_032630
• UniProt ID: Q61391