Recombinant Mouse Mgmt Protein, Myc/DDK-tagged

Cat.No. : Mgmt-4062M
Product Overview : Purified recombinant protein of mouse full-length O-6-methylguanine-DNA methyltransferase (Mgmt), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Species : Mouse
Source : HEK293
Tag : DDK&Myc
Description : Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Molecular Mass : 22.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Mgmt O-6-methylguanine-DNA methyltransferase [ Mus musculus (house mouse) ]
Official Symbol Mgmt
Synonyms MGMT; O-6-methylguanine-DNA methyltransferase; methylated-DNA--protein-cysteine methyltransferase; O-6-alkylguanine-DNA alkyltransferase; O-6-methylguanine-DNA-alkyltransferase; 6-O-methylguanine-DNA methyltransferase; AGT; Agat; AI267024; MGC107020
Gene ID 17314
mRNA Refseq NM_008598
Protein Refseq NP_032624
UniProt ID P26187

Not For Human Consumption!

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