Recombinant Human O-6-methylguanine-DNA Methyltransferase, T7-tagged
Cat.No. : | MGMT-814H |
Product Overview : | Recombinant MGMT protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 21646Da (207aa). |
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Species : | Human |
Source : | E.coli |
Tag : | T7 |
Description : | Methylated-DNA-protein-cysteine methyltransferase is an enzyme that in humans is encoded by the MGMT gene. |
Sequences of amino acids : | MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEEP VPALHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN |
Formulation : | 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3 |
Purity : | > 95% by SDS - PAGE |
Applications : | MS. SDS |
Gene Name | MGMT O-6-methylguanine-DNA methyltransferase [Homo sapiens] |
Synonyms | MGMT; O-6-methylguanine-DNA methyltransferase; methylated-DNA-protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; EC2.1.1.63; O6-methylguanine-DNA methyltransferase |
Gene ID | 4255 |
mRNA Refseq | NM_002412 |
Protein Refseq | NP_002403 |
MIM | 156569 |
UniProt ID | P16455 |
Chromosome Location | 10q26 |
Pathway | Reactome Event: DNA Repair |
Function | DNA binding; DNA-methyltransferase activity; metal ion binding; methylated-DNA-[protein]-cystein S-methyltransferase activity; methyltransferase activity; transferase activity |
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Not For Human Consumption!
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