Recombinant Mouse Mgme1 Protein, Myc/DDK-tagged

Cat.No. : Mgme1-4061M
Product Overview : Purified recombinant protein of mouse full-length mitochondrial genome maintenance exonuclease 1 (Mgme1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
  • Download
Species : Mouse
Source : HEK293
Tag : Myc&DDK
Description : Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
Molecular Mass : 38.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Mgme1 mitochondrial genome maintenance exonuclease 1 [ Mus musculus (house mouse) ]
Official Symbol Mgme1
Synonyms Mgme1; mitochondrial genome maintenance exonuclease 1; AI426476; 8430406I07Rik; mitochondrial genome maintenance exonuclease 1; mitochondrial genome maintainance exonuclease 1
Gene ID 74528
mRNA Refseq NM_028984
Protein Refseq NP_083260
UniProt ID Q9CXC3

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All Mgme1 Products

Required fields are marked with *

My Review for All Mgme1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon