Recombinant Mouse Mfrp Protein, Myc/DDK-tagged

• Cat.No.: Mfrp-4059M
• Product Overview: Purified recombinant protein of mouse full-length membrane frizzled-related protein (Mfrp), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene contains a region with similarity to the cysteine-rich domain (CRD) of frizzled, a gene originally found in Drosophila that controls tissue polarity. This protein functions in eye development, where it is necessary for the maintenance of photoreceptor outer segments. Mutations in this gene cause retinal degeneration 6 in mice, which gives rise to a mouse model for human retinitis punctata albescens. Bicistronic transcripts composed of the coding sequences for this gene (Mfrp) and the C1q and tumor necrosis factor related protein 5 gene (C1qtnf5) have been identified, and the resulting products can interact with each other. Co-transcription of C1qtnf5 and Mfrp has been observed in both human and mouse. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 63.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mfrp membrane frizzled-related protein [ Mus musculus (house mouse) ]
• Official Symbol: Mfrp
• Synonyms: MFRP; membrane-type frizzled-related protein; membrane frizzled-related protein; rd6
• Gene ID: 259172
• mRNA Refseq: NM_147126
• Protein Refseq: NP_667337
• UniProt ID: Q8K480