Recombinant Mouse Mc4r Protein, Myc/DDK-tagged

• Cat.No.: Mc4r-3987M
• Product Overview: Purified recombinant protein of mouse full-length melanocortin 4 receptor (Mc4r), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the melanocortin receptor family. Melanocortin receptors are transmembrane G-protein coupled receptors, which respond to small peptide hormones and exhibit diverse functions and tissue type localization. As part of the central nervous melanocortin system, the encoded protein is competitively bound by either melanocyte stimulating hormone or agouti-related protein to regulate energy homeostasis. Disruption of this gene promotes hyperphagia and obesity, and is associated with increased cholesterol levels and insulin resistance.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 37 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mc4r melanocortin 4 receptor [ Mus musculus (house mouse) ]
• Official Symbol: Mc4r
• Synonyms: MC4R; melanocortin 4 receptor; melanocortin receptor 4; MC4-R; Glu3; Fatboy
• Gene ID: 17202
• mRNA Refseq: NM_016977
• Protein Refseq: NP_058673
• UniProt ID: P56450