Recombinant Mouse Macroh2a1 Protein, Myc/DDK-tagged
Cat.No. : | Macroh2a1-3346M |
Product Overview : | Purified recombinant protein of mouse full-length H2A histone family, member Y (H2afy), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | Myc&DDK |
Description : | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Molecular Mass : | 39.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Macroh2a1 macroH2A.1 histone [ Mus musculus (house mouse) ] |
Official Symbol | Macroh2a1 |
Synonyms | Macroh2a1; macroH2A.1 histone; H2af; mH2a; H2afy; mH2a1; H2AF12; H2AF12M; MACROH2; core histone macro-H2A.1; H2A histone family, member Y; H2A.y; H2A/y; MACROH2A1.2; histone macroH2A1 |
Gene ID | 26914 |
mRNA Refseq | NM_001159515 |
Protein Refseq | NP_001152987 |
UniProt ID | Q9QZQ8 |
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Not For Human Consumption!
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