Recombinant Mouse Lsm5 Protein, Myc/DDK-tagged

• Cat.No.: Lsm5-3857M
• Product Overview: Purified recombinant protein of mouse full-length LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
• Molecular Mass: 10.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated [ Mus musculus (house mouse) ]
• Official Symbol: Lsm5
• Synonyms: LSM5; LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm5; 2010208O10Rik; 2310034K10Rik
• Gene ID: 66373
• mRNA Refseq: NM_025520
• Protein Refseq: NP_079796
• UniProt ID: P62322