LSM5
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Official Full Name
LSM5 homolog, U6 small nuclear RNA associated -
Overview
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. -
Synonyms
LSM5;LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae);U6 snRNA-associated Sm-like protein LSm5;YER146W;FLJ12710
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
LSM5 involved in several pathways and played different roles in them. We selected most pathways LSM5 participated on our site, such as RNA degradation,Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | RQCD1,BTG2,CNOT3A,EXOSC3,PFKM,EXOSC2,EXOSC7,ENO1A,XRN2,DHX36 |
| Spliceosome | PRPF6,XAB2,SF3B2,TRA2A,U2AF2,PRPF18,CHERP,PRPF40A,SRSF10,SNRPG |
Protein Function
LSM5 has several biochemical functions, for example, RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM5 itself. We selected most functions LSM5 had, and list some proteins which have the same functions with LSM5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | SRSF12,ATXN1A,RNMTL1A,IFIT3,KIN,PUS3,SNRNP70,DAZAP1,KHDC3L,RNASEL3 |
| protein binding | C21orf7,MYOZ1,COBL,PRKCI,ATG9A,HAX1,NOXO1,POU2AF1,CALM3,FZD10 |
Interacting Protein
LSM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM5.
SNRPF;LSM6;LSM7
Resources
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References
- Cui, P; Zhang, SD; et al. Dynamic regulation of genome-wide pre-mRNA splicing and stress tolerance by the Sm-like protein LSm5 in Arabidopsis. GENOME BIOLOGY 15:-(2014).
- Perez-Santangelo, S; Mancini, E; et al. Role for LSM genes in the regulation of circadian rhythms. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:15166-15171(2014).
