Recombinant Mouse Lmcd1 Protein, Myc/DDK-tagged

• Cat.No.: Lmcd1-3801M
• Product Overview: Purified recombinant protein of mouse full-length LIM and cysteine-rich domains 1 (Lmcd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
• Molecular Mass: 41 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lmcd1 LIM and cysteine-rich domains 1 [ Mus musculus (house mouse) ]
• Official Symbol: Lmcd1
• Synonyms: LMCD1; LIM and cysteine-rich domains 1; LIM and cysteine-rich domains protein 1; dyxin; AW455500; AW553074; MGC29184
• Gene ID: 30937
• mRNA Refseq: NM_144799
• Protein Refseq: NP_659048
• UniProt ID: Q8VEE1