Recombinant Mouse Lgmn Protein (Val18-Tyr435), C-His tagged

• Cat.No.: Lgmn-6749M
• Product Overview: Recombinant mouse Lgmn (Val18-Tyr435) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: His
• Protein Length: Val18-Tyr435
• Description: This gene encodes a member of the cysteine peptidase family C13 that plays an important role in the endosome/lysosomal degradation system. The encoded inactive preproprotein undergoes autocatalytic removal of the C-terminal inhibitory propeptide to generate the active endopeptidase that cleaves protein substrates on the C-terminal side of asparagine residues. Mice lacking the encoded protein exhibit defects in the lysosomal processing of proteins resulting in their accumulation in the lysosomes, and develop symptoms resembling hemophagocytic lymphohistiocytosis.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 51.42 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Lgmn legumain [ Mus musculus (house mouse) ]
• Official Symbol: Lgmn
• Synonyms: Lgmn; legumain; AEP; Prsc1
• Gene ID: 19141
• mRNA Refseq: NM_011175
• Protein Refseq: NP_035305
• UniProt ID: O89017