Recombinant Mouse Kif2c Protein, Myc/DDK-tagged

• Cat.No.: Kif2c-3693M
• Product Overview: Purified recombinant protein of mouse full-length kinesin family member 2C (Kif2c), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment.
• Molecular Mass: 81.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Kif2c kinesin family member 2C [ Mus musculus (house mouse) ]
• Official Symbol: Kif2c
• Synonyms: KIF2C; kinesin family member 2C; kinesin-like protein KIF2C; kinesin-like 6; mitotic centromere-associated kinesin; MCAK; ESTM5; Knsl6; X83316; 4930402F02Rik; MGC11883
• Gene ID: 73804
• mRNA Refseq: NM_134471
• Protein Refseq: NP_608301
• UniProt ID: Q922S8