Recombinant Mouse Khdc3 Protein, Myc/DDK-tagged

• Cat.No.: Khdc3-3687M
• Product Overview: Purified recombinant protein of mouse full-length KH domain containing 3, subcortical maternal complex member (Khdc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Required for maintenance of euploidy during cleavage-stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function. Capable of binding RNA.
• Molecular Mass: 48 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Khdc3 KH domain containing 3, subcortical maternal complex member [ Mus musculus (house mouse) ]
• Official Symbol: Khdc3
• Synonyms: Khdc3; KH domain containing 3, subcortical maternal complex member; F; ecat; FILIA; OEEP48; AI467128; 2410004A20Rik; KH domain-containing protein 3; protein Filia
• Gene ID: 66991
• mRNA Refseq: NM_025890
• Protein Refseq: NP_080166
• UniProt ID: Q9CWU5