Recombinant Mouse Itga6 Protein, His-tagged

• Cat.No.: Itga6-1699M
• Product Overview: Recombinant Mouse Itga6 Protein (Arg480-Arg899) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Arg480-Arg899
• Description: This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This protein has been shown to heterodimerize with beta 4 to bind laminin and to form the main component of hemidesmosomes, which mediate attachment of epithelia to basement membranes. In mouse, deficiency of this gene is associated with absence of hemidesmosomes, severe skin blistering, and early post-natal death. In humans mutations of this gene are associated with epidermolysis bullosa. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 50.9 kDa
  Accurate Molecular Mass: 53 kDa
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Itga6 integrin alpha 6 [ Mus musculus (house mouse) ]
• Official Symbol: Itga6
• Synonyms: ITGA6; integrin alpha 6; integrin alpha-6; VLA-6; CD49 antigen-like family member F; Cd49f; AI115430; 5033401O05Rik
• Gene ID: 16403
• mRNA Refseq: NM_008397
• Protein Refseq: NP_032423
• UniProt ID: Q61739