Recombinant Mouse interleukin 1, alpha, His-tagged

• Cat.No.: IL1a-640M
• Product Overview: IL1a, 115-270 aa Mouse, His tag, E.coli

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: 115-270 a.a.
• Description: IL-1a is produced by activated macrophages, stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. This protein is involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Recombinant mouse IL1a protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In Phosphate buffer saline (pH 7.4) containing 10% glycerol
• Molecular Mass: 20.4 kDa (179aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSAPYTYQ SDLRYKLMKL VRQKFVMNDS LNQTIYQDVD KHYLSTTWLN DLQQEVKFDM YAYSSGGDDS KYPVTLKISD SQLFVSAQGE DQPVLLKELP ETPKLITGSE TDLIFFWKSI NSKNYFTSAA YPELFIATKE QSRVHLARGL PSMTDFQIS
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Il1a interleukin 1 alpha [ Mus musculus ]
• Official Symbol: IL1a
• Synonyms: IL1A; interleukin 1 alpha; interleukin-1 alpha; IL-1 alpha; Il-1a
• Gene ID: 16175
• mRNA Refseq: NM_010554
• Protein Refseq: NP_034684
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis signaling pathway, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response (BioCarta), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem
• Function: copper ion binding; cytokine activity; interleukin-1 receptor binding