Recombinant Mouse Il1rn, His-tagged
| Cat.No. : | Il1rn-15856M |
| Product Overview : | Recombinant mouse IL1RN protein, fused to His tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Description : | Interleukin 1 receptor antagonist (IL1RN), also known as IL1-RA, is a member of the interleukin 1 cytokine family. IL1RN may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is no limit the pro-inflammatory signals but most prominently by mononuclear phagocytes and keratinocytes. IL1RN is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. |
| Source : | E. coli |
| Species : | Mouse |
| Tag : | His |
| Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol |
| Molecular Mass : | 20.0 kDa (177aa), confirmed by MALDI-TOF |
| Protein length : | 27-178aa |
| AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMRPSGK RPCKMQAFRI WDTNQKTFYL RNNQLIAGYL QGPNIKLEEK IDMVPIDLHS VFLGIHGGKL CLSCAKSGDD IKLQLEEVNI TDLSKNKEED KRFTFIRSEK GPTTSFESAA CPGWFLCTTL EADRPVSLTN TPEEPLIVTK FYFQEDQ |
| Purity : | >95% by SDS - PAGE |
| Applications : | SDS-PAGE |
| Storage : | Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Concentration : | 1 mg/ml (determined by Bradford assay) |
| Gene Name | Il1rn interleukin 1 receptor antagonist [ Mus musculus ] |
| Official Symbol | IL1RN |
| Synonyms | IL1RN; interleukin 1 receptor antagonist; interleukin-1 receptor antagonist protein; IRAP; IL-1RN; IL1 inhibitor; IL-1ra; F630041P17Rik; |
| Gene ID | 16181 |
| mRNA Refseq | NM_001039701 |
| Protein Refseq | NP_001034790 |
| Pathway | IL-1 Signaling Pathway, organism-specific biosystem; |
| Function | interleukin-1 Type I receptor antagonist activity; interleukin-1 Type II receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor binding; interleukin-1, Type I receptor binding; interleukin-1, Type II receptor binding; receptor activity; |
Not For Human Consumption!
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