Recombinant Mouse Hps4 Protein, Myc/DDK-tagged

• Cat.No.: Hps4-3436M
• Product Overview: Purified recombinant protein of mouse full-length HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 (Hps4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.
• Molecular Mass: 72.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 [ Mus musculus (house mouse) ]
• Official Symbol: Hps4
• Synonyms: HPS4; Hermansky-Pudlak syndrome 4 homolog (human); Hermansky-Pudlak syndrome 4 protein homolog; light ear; light-ear protein; le; BLOC-3; AU040608; mKIAA1667; 2010205O06Rik; C130020P05Rik
• Gene ID: 192232
• mRNA Refseq: NM_138646
• Protein Refseq: NP_619587
• UniProt ID: Q99KG7