Recombinant Mouse Hook1 Protein, Myc/DDK-tagged

• Cat.No.: Hook1-3428M
• Product Overview: Purified recombinant protein of mouse full-length hook microtubule tethering protein 1 (Hook1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 84.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hook1 hook microtubule tethering protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Hook1
• Synonyms: HOOK1; hook homolog 1 (Drosophila); protein Hook homolog 1; mHK1; abnormal spermatozoon head shape; azh; A930033L17Rik
• Gene ID: 77963
• mRNA Refseq: NM_030014
• Protein Refseq: NP_084290
• UniProt ID: Q8BIL5