Recombinant Mouse Hmox1 protein, His & S-tagged

• Cat.No.: Hmox1-2605M
• Product Overview: Recombinant Mouse Hmox1 aa. (Pro99~Arg237 (Accession # P14901)) fused with N-terminal His & S tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His&S
• Form: Freeze-dried powder
• Molecular Mass: 21.6 kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Pro99~Arg237
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >97%
• Characteristic: The isoelectric point is 6.26.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH 7.4.
• Reconstitution: Reconstitute in PBS.

Gene Information

• Gene Name: Hmox1 heme oxygenase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Hmox1
• Synonyms: Hmox1; heme oxygenase 1; HO1; HO-1; Hmox; Hemox; Hsp32; D8Wsu38e; heme oxygenase 1; P32 protein; heme oxygenase (decycling) 1; hemoxygenase
• Gene ID: 15368
• mRNA Refseq: NM_010442.2
• Protein Refseq: NP_034572.1
• UniProt ID: P14901

Reviews

10/03/2021

A reliable source for top-notch proteins. Fast shipping is a big plus.

04/14/2020

Exceptional service! This product has become a staple in our lab.

09/30/2018

Impressed with the product's quality. Shipping is always on time.

Q&As

Can you discuss the role of HMOX1 in modulating the immune response in the context of infectious diseases, and how its induction may impact host-pathogen interactions?

HMOX1 modulates the immune response during infectious diseases, influencing host-pathogen interactions. Its induction can contribute to an anti-inflammatory environment and impact the outcome of infections.

How does HMOX1 contribute to the regulation of iron homeostasis, and what are the molecular mechanisms involved in its interaction with iron-responsive elements?

HMOX1 regulates iron homeostasis by releasing free iron during heme degradation. Its interaction with iron-responsive elements influences cellular iron levels and responses to iron availability.

What is the relationship between HMOX1 and oxidative stress-induced autophagy, and how does this connection influence cellular responses to stressors?

HMOX1 is linked to oxidative stress-induced autophagy, contributing to cellular adaptation and survival. This connection influences the cellular response to stressors by promoting self-cleaning mechanisms.

Can you discuss the role of HMOX1 in vascular health and its impact on endothelial function, particularly in the context of cardiovascular diseases?

HMOX1 plays a role in vascular health by protecting endothelial cells. Its anti-inflammatory and vasodilatory effects contribute to cardiovascular protection and may have implications for disease prevention.

How does HMOX1 participate in the modulation of the immune response, and what are the mechanisms by which it influences inflammatory pathways?

HMOX1 modulates the immune response by suppressing inflammation. It inhibits pro-inflammatory pathways by influencing transcription factors and inhibiting the production of inflammatory mediators.