Recombinant Mouse Havcr2 Protein (Arg20-Arg191), C-Fc tagged

• Cat.No.: Havcr2-6822M
• Product Overview: Recombinant mouse TIM-3 (Arg20-Arg191) fused with the C-terminal Fc tag was expressed in mammalian cells.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Fc
• Protein Length: Arg20-Arg191
• Description: Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and toll-like receptor signaling pathway. Located in cell surface; early endosome; and immunological synapse. Is expressed in several structures, including dorsal aorta; gut; liver; lung; and reproductive system. Human ortholog (s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2).
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 43.92 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Havcr2 hepatitis A virus cellular receptor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Havcr2
• Synonyms: Havcr2; hepatitis A virus cellular receptor 2; Tim3; TIM-3; Timd3; hepatitis A virus cellular receptor 2 homolog; HAVcr-2; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; TIMD-3
• Gene ID: 171285
• mRNA Refseq: NM_134250
• Protein Refseq: NP_599011
• UniProt ID: Q8VIM0