Recombinant Mouse Grb2 Protein, MYC/DDK-tagged

• Cat.No.: Grb2-1054M
• Product Overview: Purified recombinant protein of full-length mouse growth factor receptor bound protein 2 (Grb2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Three alternatively spliced transcript variants encoding the same protein have been found for this gene..
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 25.7 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Grb2 growth factor receptor bound protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Grb2
• Synonyms: Grb2; growth factor receptor bound protein 2; Ash; AA408164; growth factor receptor-bound protein 2; SH2/SH3 adapter GRB2; adapter protein GRB2
• Gene ID: 14784
• mRNA Refseq: NM_008163
• Protein Refseq: NP_032189
• UniProt ID: Q60631