Recombinant Mouse Gpsm2 Protein, Myc/DDK-tagged

• Cat.No.: Gpsm2-3299M
• Product Overview: Purified recombinant protein of mouse full-length G-protein signalling modulator 2 (AGS3-like, C. elegans) (Gpsm2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays an important role in mitotic spindle pole organization via its interaction with NUMA1. Required for cortical dynein-dynactin complex recruitment during metaphase. Plays a role in metaphase spindle orientation. Plays an important role in asymmetric cell divisions. Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity.
• Molecular Mass: 74.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gpsm2 G-protein signalling modulator 2 (AGS3-like, C. elegans) [ Mus musculus (house mouse) ]
• Official Symbol: Gpsm2
• Synonyms: GPSM2; G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; pins homolog (Drosophia); LGN; Pins; 6230410J09Rik
• Gene ID: 76123
• mRNA Refseq: NM_029522
• Protein Refseq: NP_083798
• UniProt ID: Q8VDU0