Recombinant Mouse Gli1 Protein, Myc/DDK-tagged

• Cat.No.: Gli1-3224M
• Product Overview: Purified recombinant protein of mouse full-length GLI-Kruppel family member GLI1 (Gli1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling.
• Molecular Mass: 119 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gli1 GLI-Kruppel family member GLI1 [ Mus musculus (house mouse) ]
• Official Symbol: Gli1
• Synonyms: GLI1; GLI-Kruppel family member GLI1; zinc finger protein GLI1; zinc finger protein 5; glioma-associated oncogene homolog; Zfp5; Zfp-5; AV235269
• Gene ID: 14632
• mRNA Refseq: NM_010296
• Protein Refseq: NP_034426
• UniProt ID: P47806