Recombinant Mouse Gga2 Protein, Myc/DDK-tagged

• Cat.No.: Gga2-3198M
• Product Overview: Purified recombinant protein of mouse full-length golgi associated, gamma adaptin ear containing, ARF binding protein 2 (cDNA clone MGC:67474 IMAGE:5698559),, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network.
• Molecular Mass: 38.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gga2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Gga2
• Synonyms: Gga2; golgi associated, gamma adaptin ear containing, ARF binding protein 2; mKIAA1080; 1200007E24Rik; ADP-ribosylation factor-binding protein GGA2; gamma-adaptin-related protein 2; golgi-localized, gamma ear-containing, ARF-binding protein 2
• Gene ID: 74105
• mRNA Refseq: NM_028758
• Protein Refseq: NP_083034
• UniProt ID: Q6P5E6