Recombinant Mouse Gdf15 protein, His-tagged

• Cat.No.: Gdf15-392M
• Product Overview: Recombinant Mouse GDF15 fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Description: Growth/differentiation factor 15, also known as GDF15, is a member of the TGF superfamily. It has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
• Form: Liquid. In 20mM Phosphate buffer (pH 8.0) containing 10% glycerol.
• Molecular Mass: 14.9 kDa (138aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSAHAHPR DSCPLGPGRC CHLETVQATL EDLGWSDWVL SPRQLQLSMC VGECPHLYRS ANTHAQIKARLHGLQPDKVP APCCVPSSYT PVVLMHRTDS GVSLQTYDDL VARGCHCA
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Gdf15 growth differentiation factor 15 [ Mus musculus ]
• Official Symbol: Gdf15
• Synonyms: GDF15; growth differentiation factor 15; growth/differentiation factor 15; GDF-15; macrophage inhibiting cytokine-1; SBF; MIC-1; NAG-1
• Gene ID: 23886
• mRNA Refseq: NM_011819
• Protein Refseq: NP_035949
• Function: growth factor activity