Recombinant Mouse Fus Protein, Myc/DDK-tagged
Cat.No. : | Fus-3107M |
Product Overview : | Purified recombinant protein of mouse full-length fused in sarcoma (Fus), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. Binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc&DDK |
Molecular Mass : | 53.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Fus fused in sarcoma [ Mus musculus (house mouse) ] |
Official Symbol | Fus |
Synonyms | FUS; fusion, derived from t(12;16) malignant liposarcoma (human); RNA-binding protein FUS; hnRNP P2; pigpen protein; protein pigpen; translocated in liposarcoma; Tls; Fus1; D430004D17Rik; D930039C12Rik |
Gene ID | 233908 |
mRNA Refseq | NM_139149 |
Protein Refseq | NP_631888 |
UniProt ID | P56959 |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Q&As (0)
Ask a questionAsk a Question for All Fus Products
Required fields are marked with *
My Review for All Fus Products
Required fields are marked with *
0
Inquiry Basket