Recombinant Mouse Fmo3 Protein, Myc/DDK-tagged

• Cat.No.: Fmo3-3054M
• Product Overview: Purified recombinant protein of mouse full-length flavin containing monooxygenase 3 (Fmo3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.
• Molecular Mass: 61 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fmo3 flavin containing monooxygenase 3 [ Mus musculus (house mouse) ]
• Official Symbol: Fmo3
• Synonyms: FMO3; flavin containing monooxygenase 3; dimethylaniline monooxygenase [N-oxide-forming] 3; FMO 3; dimethylaniline oxidase 3; hepatic flavin-containing monooxygenase 3; AW111792
• Gene ID: 14262
• mRNA Refseq: NM_008030
• Protein Refseq: NP_032056
• UniProt ID: P97501