Recombinant Mouse Flna Protein, Myc/DDK-tagged

• Cat.No.: Flna-3038M
• Product Overview: Purified recombinant protein of mouse full-length filamin, alpha (Flna), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Broad expression in bladder adult (RPKM 809.2), ovary adult (RPKM 279.4) and 17 other tissues.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 280.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Flna filamin, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Flna
• Synonyms: FLNA; filamin, alpha; filamin-A; FLN-A; GENA 379; filamin A; alpha-filamin; dilated pupils 2; non-muscle filamin; actin-binding protein 280; endothelial actin-binding protein; Fln1; Dilp2; ABP-280; filamin-1; F730004A14Rik
• Gene ID: 192176
• mRNA Refseq: NM_010227
• Protein Refseq: NP_034357
• UniProt ID: B7FAU9

Reviews

11/28/2021

The structure is stable and not prone to mutations.

10/09/2021

Simplify complex chemical reactions and increase yields and reduce experimental time.

02/23/2021

The combination of strong biological activity and high purity results in extremely reliable results.

Q&As

How can FLNA expression levels be measured?

FLNA expression levels can be detected by gene sequencing, immunohistochemistry, and western blotting.

What might be involved in future research on FLNA?

Future research on FLNA may involve more in-depth research on molecular mechanisms, new drug development, and targeted therapy strategies based on FLNA. In addition, studies may also address the function and mechanism of action of FLNA in other tissues and organs.

Does FLNA interact with other molecules or drugs?

There are multiple interactions between FLNA and other molecules and drugs. For example, FLNA can bind to actin, affecting cell migration and morphology. In addition, some drugs can also affect FLNA expression levels or function.

Are there population differences in FLNA treatment?

It is unclear whether there is a population difference in the treatment of FLNA. However, due to factors such as individual differences and genetic polymorphisms, different populations may respond differently to treatment. Therefore, population-specific treatment strategies may need to be individually adapted and optimized.

What is the treatment of FLNA?

There is currently no specific treatment for FLNA. However, drugs that target their associated signal transduction pathways or binding targets may have potential therapeutic value.

Can FLNA expression level be used as a biomarker for disease diagnosis or prognosis?

Current research on FLNA expression levels as a biomarker for disease diagnosis or prognosis is insufficient and further validation is needed.