Recombinant Human FLNA protein, His&Myc-tagged

• Cat.No.: FLNA-2923H
• Product Overview: Recombinant Human FLNA protein(P21333)(2-274aa), fused to N-terminal His tag and C-terminal Myc tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His&Myc
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
  If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 38.0 kDa
• Protein length: 2-274aa
• AA Sequence: SSSHSRAGQSAAGAAPGGGVDTRDA EMPATEKDLAEDAPWKKIQQNTFTR WCNEHLKCVSKRIANLQTDLSDGLR LIALLEVLSQKKMHRKHNQRPTFRQ MQLENVSVALEFLDRESIKLVSIDS KAIVDGNLKLILGLIWTLILHYSIS MPMWDEEEDEEAKKQTPKQRLLGWI QNKLPQLPITNFSRDWQSGRALGAL VDSCAPGLCPDWDSWDASKPVTNAR EAMQQADDWLGIPQVITPEEIVDPN VDEHSVMTYLSQFPKAKLKPGAP
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

Gene Information

• Gene Name: FLNA filamin A, alpha [ Homo sapiens ]
• Official Symbol: FLNA
• Synonyms: FLNA; filamin A, alpha; filamin A, alpha (actin binding protein 280) , FLN, FLN1, OPD1, OPD2; filamin-A; ABP 280; actin binding protein 280; filamin-1; alpha-filamin; non-muscle filamin; endothelial actin-binding protein; FLN; FMD; MNS; OPD; ABPX; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280; FLJ43642; DKFZp434P031
• Gene ID: 2316
• mRNA Refseq: NM_001110556
• Protein Refseq: NP_001104026
• MIM: 300017
• UniProt ID: P21333

Reviews

11/28/2021

The structure is stable and not prone to mutations.

10/09/2021

Simplify complex chemical reactions and increase yields and reduce experimental time.

02/23/2021

The combination of strong biological activity and high purity results in extremely reliable results.

Q&As

How can FLNA expression levels be measured?

FLNA expression levels can be detected by gene sequencing, immunohistochemistry, and western blotting.

What might be involved in future research on FLNA?

Future research on FLNA may involve more in-depth research on molecular mechanisms, new drug development, and targeted therapy strategies based on FLNA. In addition, studies may also address the function and mechanism of action of FLNA in other tissues and organs.

Does FLNA interact with other molecules or drugs?

There are multiple interactions between FLNA and other molecules and drugs. For example, FLNA can bind to actin, affecting cell migration and morphology. In addition, some drugs can also affect FLNA expression levels or function.

Are there population differences in FLNA treatment?

It is unclear whether there is a population difference in the treatment of FLNA. However, due to factors such as individual differences and genetic polymorphisms, different populations may respond differently to treatment. Therefore, population-specific treatment strategies may need to be individually adapted and optimized.

What is the treatment of FLNA?

There is currently no specific treatment for FLNA. However, drugs that target their associated signal transduction pathways or binding targets may have potential therapeutic value.

Can FLNA expression level be used as a biomarker for disease diagnosis or prognosis?

Current research on FLNA expression levels as a biomarker for disease diagnosis or prognosis is insufficient and further validation is needed.