Recombinant Mouse Fkbp4 Protein, Myc/DDK-tagged

• Cat.No.: Fkbp4-3027M
• Product Overview: Purified recombinant protein of mouse full-length FK506 binding protein 4 (Fkbp4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
• Molecular Mass: 52 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fkbp4 FK506 binding protein 4 [ Mus musculus (house mouse) ]
• Official Symbol: Fkbp4
• Synonyms: FKBP4; FK506 binding protein 4; peptidyl-prolyl cis-trans isomerase FKBP4; HBI; FKBP59; rotamase; 52 kDa FKBP; PPIase FKBP4; 59 kDa immunophilin; immunophilin FKBP52; FK506-binding protein 4; HSP-binding immunophilin; 52 kDa FK506-binding protein; p59; 59kDa; FKBP-4; FKBP52; FKPB52; FKBP-52; AL022792; AW208983
• Gene ID: 14228
• mRNA Refseq: NM_010219
• Protein Refseq: NP_034349
• UniProt ID: P30416