Recombinant Mouse Fis1 Protein, Myc/DDK-tagged

• Cat.No.: Fis1-3017M
• Product Overview: Purified recombinant protein of mouse full-length fission, mitochondrial 1 (Fis1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. May be not essential for the assembly of functional fission complexes and the subsequent membrane scission event. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
• Molecular Mass: 17 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fis1 fission, mitochondrial 1 [ Mus musculus (house mouse) ]
• Official Symbol: Fis1
• Synonyms: FIS1; fission 1 (mitochondrial outer membrane) homolog (yeast); mitochondrial fission 1 protein; FIS1 homolog; TPR repeat protein 11; tetratricopeptide repeat domain 11; tetratricopeptide repeat protein 11; Ttc11; 2010003O14Rik
• Gene ID: 66437
• mRNA Refseq: NM_025562
• Protein Refseq: NP_079838
• UniProt ID: Q9CQ92