Recombinant Mouse Fem1b Protein, Myc/DDK-tagged

• Cat.No.: Fem1b-2985M
• Product Overview: Purified recombinant protein of mouse full-length feminization 1 homolog b (C. elegans) (Fem1b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
• Molecular Mass: 70.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fem1b fem 1 homolog b [ Mus musculus (house mouse) ]
• Official Symbol: Fem1b
• Synonyms: FEM1B; feminization 1 homolog b (C. elegans); protein fem-1 homolog B; mt-Fem; F1A-alpha; FEM1-beta; fem-1-like in apoptotic pathway protein alpha; fem-1-like death receptor-binding protein alpha; mKIAA0396
• Gene ID: 14155
• mRNA Refseq: NM_010193
• Protein Refseq: NP_034323
• UniProt ID: Q9Z2G0