Recombinant Mouse Faf2 Protein, Myc/DDK-tagged

• Cat.No.: Faf2-2906M
• Product Overview: Purified recombinant protein of mouse full-length Fas associated factor family member 2 (Faf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 52.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Faf2 Fas associated factor family member 2 [ Mus musculus (house mouse) ]
• Official Symbol: Faf2
• Synonyms: FAF2; Fas associated factor family member 2; FAS-associated factor 2; UBX domain containing 8; UBX domain-containing protein 8; protein expressed in T-cells and eosinophils in atopic dermatitis; Ubxd8; AI462440; mKIAA0887; 2210404D11Rik
• Gene ID: 76577
• mRNA Refseq: NM_178397
• Protein Refseq: NP_848484
• UniProt ID: Q3TDN2