FAF2
-
Official Full Name
Fas associated factor family member 2 -
Overview
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. -
Synonyms
FAF2;Fas associated factor family member 2;UBX domain containing 8 , UBXD8;FAS-associated factor 2;ETEA;expressed in T cells and eosinophils in atopic dermatitis;KIAA0887;UBX domain protein 3B;UBXN3B;AI462440;Protein expressed in T cells and eosinophils in atopic dermatitis;Protein expressed in T-cells and eosinophils in atopic dermatitis;UBX domain containing 8;UBXD8;OTTHUMP00000223381;UBX domain-containing protein 8;UBX domain-containing protein 3B;expressed in T-cells and eosinophils in atopic dermatitis
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
FAF2 involved in several pathways and played different roles in them. We selected most pathways FAF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FAF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FAF2 has several biochemical functions, for example, lipase binding,lipase inhibitor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAF2 itself. We selected most functions FAF2 had, and list some proteins which have the same functions with FAF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase binding | RFFL,PRKACB,BRCA1,PIAS4,JKAMP,GPR37,BLZF1,UBE2B,EIF4E2,TRAF3 |
| lipase binding | PLIN5,GPIHBP1,APOB,APOA5,LRPAP1 |
| protein binding | TADA3,IGF1,HBD,PAIP2,C9orf16,ADAMTSL3,RMND5A,ARIH2,SEC24A,USP6 |
| ubiquitin binding | UBXN11,UBE2NB,DNAJC2,SMAD3,VPS28,RNF31,NSFL1C,NBR1,UBR5,DYRK2 |
| lipase inhibitor activity | APOC1,APOA1,APOC3,APOA2,APOC2 |
Interacting Protein
FAF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAF2.
VCPIP1;UBA1;UBE2N;UBE2V1;Map3k1;RGS20;UBL4A;USP13;15-deoxy-delta(12,14;PJA2;STK17B;UBR5;MYC;1C;UBB;HSPA5;Insr
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