Recombinant Mouse Faap20 Protein, Myc/DDK-tagged

• Cat.No.: Faap20-2903M
• Product Overview: Purified recombinant protein of mouse full-length Fanconi anemia core complex associated protein 20 (Faap20), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.
• Molecular Mass: 20.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Faap20 Fanconi anemia core complex associated protein 20 [ Mus musculus (house mouse) ]
• Official Symbol: Faap20
• Synonyms: Faap20; Fanconi anemia core complex associated protein 20; 2610002J02Rik; Fanconi anemia core complex-associated protein 20; FANCA-associated protein of 20 kDa; Fanconi anemia-associated protein of 20 kDa; likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86)
• Gene ID: 67513
• mRNA Refseq: NM_001190445
• Protein Refseq: NP_001177374
• UniProt ID: Q3UN58