Recombinant Mouse F11r Protein, Myc/DDK-tagged

• Cat.No.: F11r-2899M
• Product Overview: Purified recombinant protein of mouse full-length F11 receptor (F11r), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation.
• Molecular Mass: 32.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: F11r F11 receptor [ Mus musculus (house mouse) ]
• Official Symbol: F11r
• Synonyms: F11R; F11 receptor; junctional adhesion molecule A; BV11 antigen; F11 receptor/F11R; junctional adhesion molecule 1; junction cell adhesion molecule1; junction cell adhesion molecule A; JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; AA638916; 9130004G24
• Gene ID: 16456
• mRNA Refseq: NM_172647
• Protein Refseq: NP_766235
• UniProt ID: O88792