Recombinant Mouse Esyt2 Protein, Myc/DDK-tagged

• Cat.No.: Esyt2-2877M
• Product Overview: Purified recombinant protein of mouse full-length extended synaptotagmin-like protein 2 (Esyt2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS).
• Molecular Mass: 94.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Esyt2 extended synaptotagmin-like protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Esyt2
• Synonyms: ESYT2; extended synaptotagmin-like protein 2; extended synaptotagmin-2; E-Syt2; chr2 synaptotagmin; family with sequence similarity 62, member B; family with sequence similarity 62 (C2 domain containing), member B; Fam62b; CHR2SYT; D12Ertd551e; 2410017M09Rik; 4921504I16Rik; KIAA1228
• Gene ID: 52635
• mRNA Refseq: NM_028731
• Protein Refseq: NP_083007
• UniProt ID: Q3TZZ7