Recombinant Mouse Esrra Protein, Myc/DDK-tagged

• Cat.No.: Esrra-2873M
• Product Overview: Purified recombinant protein of mouse full-length estrogen related receptor, alpha (Esrra), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 45.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Esrra estrogen related receptor, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Esrra
• Synonyms: ESRRA; estrogen related receptor, alpha; steroid hormone receptor ERR1; ERR-alpha; estrogen receptor-like 1; estrogen receptor related 1; estrogen-related receptor alpha; nuclear receptor subfamily 3 group B member 1; Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1); Err1; Nr3b1; Estrra; ERRalpha
• Gene ID: 26379
• mRNA Refseq: NM_007953
• Protein Refseq: NP_031979
• UniProt ID: O08580